University physicists Leonard and Sheldon know whether to use an integral or a differential to solve the area under a curve. But they don't have a clue about girls. Or dating. Or clothes. Or parties. Or having fun. Or, basically, life. So when a pretty blonde named Penny moves in the apartment across the hall, the guys decide to get an education outside of the classroom. Boys, you have a lot to learn.

• Johnny Galecki
• Jim Parsons
• Kaley Cuoco
• Simon Helberg
• Kunal Nayyar
• Melissa Rauch
• Mayim Bialik